Abstract
BackgroundAdrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. ACCs are classified as functioning and non-functioning. The pathogenesis of ACC remains elusive, and diagnosis of ACC is currently based on pathology. In the absence of other effective approaches, surgical resection is the preferred treatment option.Case presentationHere, we report a case of ACC in the retroperitoneum. The patient underwent radical adrenalectomy and remained disease-free throughout a 6-month follow-up.ConclusionsRadical surgical resection is an efficient therapy for ACC, and hydrocortisone can be used to alleviate symptoms of secondary acute adrenal hypofunction.
Highlights
Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis
The patient was treated with left radical adrenalectomy and followed up with physical assessments, laboratory testing, and imaging, including X-rays and computed tomography (CT) scans
We report the case of a 31-year-old female who underwent radical surgical resection of a mixed solid and cystic lesion in the left upper quadrant of the abdomen
Summary
Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a very poor prognosis. The patient was treated with left radical adrenalectomy and followed up with physical assessments, laboratory testing, and imaging, including X-rays and computed tomography (CT) scans. The patient had undergone two cesarean sections in January 2006 and June 2015 and had a 12-cm postoperative scar on the lower abdomen She had a large palpable mass in the left abdomen. Histological staining of sections of resected tumor certificated the diagnosis of ACC [Fig. 3]. The patient’s symptoms were assumed to be caused by secondary acute adrenal hypofunction This was confirmed by measuring serum cortisol levels, which were 152.55 nmol/l at 00:00(normal, 240–619 nmol/l), 177.37 nmol/l at 08:00(normal, 240–619 nmol/l), and 139.1 nmol/l at 16:00 (normal, < 276 nmol/l). The patient underwent regular follow-up with physical assessments, laboratory testing, and imaging, including X-rays and computed CT scans. At the 6-month follow-up, she remained disease-free
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