Abstract

二甲双胍致肝功能损伤较少见。本文报道1例老年新发糖尿病患者口服二甲双胍缓释片(500 mg/d)治疗2个月后出现乏力、厌食、恶心等症状,伴血清丙氨酸氨基转移酶和天冬氨酸氨基转移酶水平升高,排除恶性肿瘤、病毒性肝炎、自身免疫性肝病,诊断为口服二甲双胍缓释片致急性药物性肝损伤。停药后症状消失,肝功能恢复正常。

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