Abstract
Low frequency of rare diseases origins from missed diagnosis addressing to poor prognosis. Acquired factor V inhibitor is a very low frequent bleeding condition (prevalence: 0.09/100,000,000–0.29/1,000,000 per year). Antibiotics, surgery, bacterial infections, malignancies, and autoimmune diseases are predisposing factors; however, no predisposing factor was found often. Authors reported a case of bleeding originating from an acquired factor V deficiency because they wish to draw attention to unfrequented or rare clinical situations rarely diagnosed in internal medicine unit.
Highlights
Factor V (FV) plays a role in clotting.[1]
FV deficiency is rare among bleeding disorders it can ensue from an inhibitor antibody
We found a very low level of FV (0.1% vs. normal value 60–140%)—no other coagulative factors were altered (►Table 1)
Summary
Factor V (FV) plays a role in clotting.[1]. FV deficiency is rare among bleeding disorders it can ensue from an inhibitor antibody. Keywords ► coagulation ► acquired inhibitors ► factor V Acquired factor V inhibitor is a very low frequent bleeding condition (prevalence: 0.09/100,000,000–0.29/1,000,000 per year). Authors reported a case of bleeding originating from an acquired factor V deficiency because they wish to draw attention to unfrequented or rare clinical situations rarely diagnosed in internal medicine unit.
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