Abstract

A case-control study evaluating association of serum vitamin D level with alopecia areata - IJCED- Print ISSN No: - 2581-4710 Online ISSN No:- 2581-4729 Article DOI No:- 10.18231/j.ijced.2019.040, IP Indian Journal of Clinical and Experimental Dermatology-IP Indian J Clin Exp Dermatol

Highlights

  • Evidance has suggested that Vitamin D may play a vital role in the pathogenesis of alopecia areata (AA)

  • Serum Vitamin D level was found to be 25.58 ± 9.82 ng/mL among subjects graded as having alopecia circumscripta

  • Levels of Vitamin D further dropped to 12.28 ± 5.06 ng/mL and 11.27 ± 5.90 ng/mL where extent of scalp involvement was graded as alopecia totalis and alopecia universalis respectively

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Summary

Introduction

Evidance has suggested that Vitamin D may play a vital role in the pathogenesis of alopecia areata (AA). Aim: To study find the correlation, if any, between Alopecia areata and levels of Vitamin D. Serum Vitamin D level was found to be 26.04±10.06 ng/mL where scalp involvement was between 0%–24%. Levels of Vitamin D further dropped to 11.91±4.18 ng/mL and 11.91±4.18 ng/mL where scalp involvement was graded as S4 and S5 respectively. Negative correlation (r = − 0.264) was noted between extent of Alopecia Areata and Vitamin D levels. Levels of Vitamin D further dropped to 12.28 ± 5.06 ng/mL and 11.27 ± 5.90 ng/mL where extent of scalp involvement was graded as alopecia totalis and alopecia universalis respectively. Vitamin D levels had inverse correlation with the pattern of alopecia in these patients.

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