A Brief Overview on Antioxidant Activity Determination of Silver Nanoparticles.

Zdenka Bedlovičová,Matej Baláž,Aneta Salayová,Imrich Strapáč

doi:10.3390/molecules25143191

Abstract

Our objective in this review article is to find out relevant information about methods of determination of antioxidant activity of silver nanoparticles. There are many studies dealing with mentioned problem and herein we summarize the knowledge about methods evaluating the antioxidant activity of silver nanoparticles reported so far. Many authors declare better antioxidant activity of silver nanoparticles compared to the extract used for synthesis of them. In this review, we focused on methods of antioxidant activity determination in detail to find out novel and perspective techniques to solve the general problems associated with the determination of antioxidant activity of silver nanoparticles.

Highlights

Nanoscience and nanotechnology have been introduced as interdisciplinary fields in biology, chemistry, physics, and bioengineering
Well characterized PVP-coated AgNPs were used in A549 cells to study reactive oxygen species production leading to programmed cell death [10]
They showed significant cytotoxicity against A549 cells caused by green synthesized AgNPs from water extract of Annemarrhena asphodeloides. These nanoparticles involved an increase in oxidative stress in A549 cells and inhibition of cell migration, but it is important to say that AgNPs do not exhibit significant toxicity to normal cell lines (3T3-L1 pre adipocyte cell lines) [11]

Summary

Introduction

Nanoscience and nanotechnology have been introduced as interdisciplinary fields in biology, chemistry, physics, and bioengineering. Another study published by Lee et al [11] was focused on cytotoxic activity in normal and cancer cell lines. They showed significant cytotoxicity against A549 cells caused by green synthesized AgNPs from water extract of Annemarrhena asphodeloides. These nanoparticles involved an increase in oxidative stress in A549 cells and inhibition of cell migration, but it is important to say that AgNPs do not exhibit significant toxicity to normal cell lines (3T3-L1 pre adipocyte cell lines) [11]

Objectives

Methods

Findings

Conclusion