A Brief Look at the Perception of Pain Management in Sickle Cell Crisis

Abstract

Submit Manuscript | http://medcraveonline.com millions of other people throughout the world, particularly those whose ancestors came from sub-Saharan Africa and Spanish speaking regions of the Western Hemisphere [1,2]. Sickle cell disease is further characterized by the production of hemoglobin S in the erythrocyte, vaso-occlusion, and hemolytic anemia. Hemoglobin S differs from normal hemoglobin A by a single amino acid substitution of valine for glutamic acid. Sickle cell disease involves multiple organ systems and acute complications. Sickle cell anemia is associated with pain episodes, micro vascular disruption of organs (spleen, liver, bone marrow, kidney, brain, and lungs), gallstones, priapism, leg ulcers and anemia. Other complications includes: ocular disease, pregnancy related problems, and anemia. Sick cell Beta-thalassemia is milder severity than sickle cell anemia because production of some hemoglobin A. Common acute complications associated with sickle cell disease includes: fever and infection, neurologic, acute chest syndrome, priapism, splenic sequestration and sickle cell pain [1-5].