Abstract

The third case of a testicular Brenner tumor is presented. Based on histologic as well as embryologic studies, a hypothesis is made which reconciles advocates of origin of the Brenner tumor from germinal epithelium (müllerian) with proponents of origin in the rete complex (wolffian) the rete tubules have been tacitly linked with mesonephric rests, but they are, in fact, probably derived from germinal epithelium, and commingling with the mesonephric system is by no means constant the ovarian Brenner tumor is thus viewed as a derivative of germinal epithelium, whether it be located over the cortical surface or lining tubules of the rete ovarii. Testicular Brenner tumors conceivably arise from known müllerian vestiges in the epididymotesticular groove.

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