Abstract

ObjectivesThe efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted. MethodsWe reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection against pulmonary TB. ResultsWe identified 15 papers reporting prospective studies and their long-term follow up, retrospective studies or systematic reviews. ConclusionsGood quality evidence supports the efficacy of BCG vaccination in the prevention of adult pulmonary tuberculosis.

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