A BIOMECHANICAL STUDY OF SHEAR LOAD ON BONE–SCREW INTERFACE OF THORACOLUMBAR VERTEBRAE

Abstract

Vertebral screw failure by cutting through or pulling out of the vertebral body is common in intraoperative and postoperative stages of anterior thoracolumbar surgery, especially in osteoporotic patients. This biomechanical study was conducted to investigate the maximum shear force thoracolumbar vertebrae can withstand and the corresponding displacement of screws and analyze their correlation with vertebral bone mineral density. Forty individual vertebra specimens (T11-L3) were obtained from eight fresh adult cadaveric thoracolumbar spine specimens and randomly divided into an experimental group and a control group. Screws were placed in the center point of vertebrae and penetrated the contralateral cortex. Shear loading and axial pullout tests were conducted on the experimental group while only axial pullout test was conducted on the control group. The maximum shear forces and maximum axial pullout forces were recorded. The conditions of vertebral body destruction and screw channel were observed and the maximum axial pullout forces were recorded and analyzed. A large amount of thread bone debris was observed in the control group. In the experimental group, however, only a small amount of thread bone debris was observed; the widths of screw paths were larger than those in the control group and gradually increased from screw tips in the direction of loading. The vertebral bodies had an average shear strength of [Formula: see text][Formula: see text]N, and the corresponding average screw displacement was [Formula: see text][Formula: see text]mm. Linear regression analysis showed that the shear strength had a significant positive correlation with vertebral bone mineral density (BMD) (r[Formula: see text][Formula: see text][Formula: see text]0.958, P[Formula: see text][Formula: see text][Formula: see text]0.01), while the screw displacement had a significant negative correlation with vertebral BMD (r[Formula: see text][Formula: see text][Formula: see text]−0.933, P[Formula: see text][Formula: see text][Formula: see text]0.01). No significant difference in bone density was found between the destruction and the control groups (P[Formula: see text][Formula: see text][Formula: see text]0.05); the difference in maximum axial pullout strength between the destruction and the control groups was significant (P[Formula: see text][Formula: see text][Formula: see text]0.01). These results indicated that vertebral BMD positively correlated with the maximum shear force and negatively with the screw displacement. It is important that the corrective strength for spinal deformity may affect bone–screw interface in anterior thoracolumbar surgery.