A biolized implantable ventricular assist device compatible with IABP console.

Abstract

A low pressure pneumatic pusher plate blood pump was developed for temporary right, left, or biventricular assist. Important features of this pump are its 1) driveability by the standard, easily available intraaortic balloon pump (IABP) console; 2) gelatin coated internal surface for blood compatibility; 3) essentially flat disc shape, 3 cm thick and 11 cm in diameter, for optimal anatomic fit; and 4) unique pusher plate guide mechanism to ensure linear motion without deflections of the diaphragm, and consequent uniform flow distribution into the pump. The guide telescopes into itself to avoid a housing protrusion for easy implantability; this controlled movement also provides a number of performance, control, and diagnostic benefits. The pump's 60 ml displacement gives up to 4.7 L/min at 80 bpm and 6.7 L/min at 120 bpm outputs in a mock loop. This VAD has been implanted in two calves for 43 to 84 days, continuously driven by a Datascope IABP console. An average 5 L/min pump output has been observed in both synchronous and fixed rate modes. No anticoagulation was required. We expect extensive clinical use of this VAD, based on its reliability, low cost, and simplicity.