Abstract
A biokinetic model for absorption and distribution of 222Rn in the body following ingestion in drinking water was developed. The rate parameters for the model are derived from historical human data reported in experiments of Harley et al. (1958) and Hursh et al. (1965). The biokinetic model fits the human data of Hursh et al. well for whole body retention following ingestion of 222Rn in water on an empty stomach. The equivalent dose to stem cells for stomach and colon cancer is estimated to be 1.6 × 10 −9 Sv Bq −1. The model calculations yield 4 and 3 calculated stomach and colon cancers from continuous intake of water at the estimated U.S. average of 5.5 Bq L −1.
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