Abstract
Pathogenic bacteria attached to medical device surfaces result in the persistence of chronic bacterial infections and pose severe threats to human health. In this study, a one-step co-deposition method was developed to fabricate tannic acid (TA)-based vanadium ions (Vn+)-phenolic network coating. The successful co-deposition of PEG-TA/Vn+ on the Ti surfaces was confirmed by Scanning electronic microscopy (SEM), Energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FITR), and X-ray photoelectron spectroscopy (XPS) analyses. The PEG-TA/Vn+ co-deposited coating showed excellent flexibility and good adhesion on various substrates. The as-prepared coating exhibited remarkable antifouling and photothermal antibacterial properties, preventing biofilm formation and scavenging the reactive oxygen species (ROS) during incubation with cells. The present work provides an efficient strategy for the design of antifouling, antibacterial, and antioxidant surface coating formulations to prevent medical device-associated infections.
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