Abstract

A bifunctional flexible glucose microsensor has been successfully fabricated by directly growing a layered double hydroxide nanosheet array (LDH-NSA) on Ni wire. The as-obtained CoFe-LDH-NSA exhibits promising performances in electrochemical and colorimetric detection of glucose with high sensitivity and selectivity. This work demonstrates an effective strategy to fabricate multi-functional glucose nonenzyme sensors.

Highlights

  • A bifunctional flexible glucose microsensor has been successfully fabricated by directly growing a layered double hydroxide nanosheet array (LDH-NSA) on Ni wire

  • For a given sensor based on monoelectrochemical detection, the fast response and readable signal to the naked eyes are hard to be simultaneously achieved, which limits its applications in qualitative self-help tests

  • Layered double hydroxides (LDHs) are layered anionic clays that are assembled by positively charged hydroxide layers ([MII1ÀxMIIIx(OH)2]z+; MII and MIII are divalent and trivalent metals) and charge compensating interlayer anions.[16,17,18]

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Summary

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A bifunctional nonenzymatic flexible glucose microsensor based on CoFe-Layered double. The TMB solution exhibits the same color change in the presence or absence of urine in the glucose solution, with a linear range from 1 mM to 20 mM and a detection limit of 0.51 mM (based on 3SD/N), indicating good peroxidase-like colorimetric activity in human urine by using CoFe-LDH. It possesses good protein anti-interference properties (Fig. S9†), indicating that the hierarchical CoFe-LDH-NSA is suitable for glucose analysis of real samples

Conclusions
Experimental section
Findings
Glucose sensor measurements
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