Abstract

Simple SummaryThis work analyzes the development of Bioinformatics research in Mexico through articles published in the last 25 years, as they have been stored in a field-specific database (PubMed). The main findings reveal that the main themes identified are strongly related to the research of outstanding researchers, the outstanding collaborations of Mexican institutions with foreign countries and institutions are influenced by the geographic proximity and binational agreements as well as philanthropic and academic programs that promote collaborations, and there is an inclination for health issues promoted by public health financing and philanthropic organizations. It is identified that publications in the field had an explosion since 2012 due to the maturity of nucleic acid sequencing technologies and the high availability of this information in public databases. Overall, this work suggests both the necessity to improve funding in this informatic discipline and promote academic collaboration inside and outside the country. Finally, the strategy used in this work allows us to make a diagnostic of the strengths and weaknesses of bioinformatics research development that can be applied in other countries. This is worth it because bioinformatics is a tool that can boost several economic sectors.Bioinformatics is a very important informatics tool for health and biological sciences, focusing on biological data management. The objective of this work was to perform a bibliometric analysis regarding the development of Mexican bioinformatics. An exhaustive revision of the literature associated with Mexican bioinformatics in a period of 25-years was performed. Bibliometric tools, such as performance analysis and science mapping were included in the analysis. We identified the main actors as well as the structure and dynamics of Mexican bioinformatics. Some of the main findings were as follows: the thematic structure in the field is defined by the research lines of outstanding authors; the outstanding collaborations of Mexican institutions with foreign countries and institutions are influenced by the geographic proximity and binational agreements, as well as philanthropic and academic programs that promote collaborations, and there is an inclination for health issues promoted by public health financing and philanthropic organizations. It is identified that publications had an explosion since 2012, we consider that this growth may be influenced by the democratization of data, derived from the mass sequencing of biological molecules stored in public databases.

Highlights

  • Bioinformatics, in its minimalist definition, is the application of computational technologies to the management and analysis of biological data [1]

  • Through the bibliometric analysis of the scientific literature, we revealed aspects associated with Mexican bioinformatics, such as the main actors and collaborations of foreign countries

  • We detected individual geographic and cultural relationships that could be favoring the collaboration of Mexican bioinformatics with other countries and binational agreements that promote the interaction of researchers with foreign Universities as in the case between the University of California and Mexican academic institutions

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Summary

Introduction

Bioinformatics, in its minimalist definition, is the application of computational technologies to the management and analysis of biological data [1]. The current omic technologies (genomics, proteomics, and metabolomics) have generated a vast amount of data without precedents in the history of biology, creating the need for their storage [4], annotation, analysis, organization and integration in biological networks and databases. These technologies have been the leading forces for the growth and development of bioinformatics in the last years [5], bioinformatics is not just about storing biological data, it concerns conducting experiments on that data. Bioinformatics is considered by several countries to be one of the main areas for the innovation of technologies related to the life sciences and of high relevance for the development of the global bio-economy [6,7,8]

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