Abstract
Approximately 10% of US children under 3 years of age will experience some degree of iron deficiency that, even in the absence of overt anemia, has the potential for causing long-term cognitive defects. Clinicians are not only faced with conflicting guidance on screening for iron deficiency but also lack a straightforward method for doing so. About three-quarters of children with iron deficiency will have nominally normal hemoglobin levels and, because of the relatively long life of erythrocytes, changes in the traditional red cell indices associated with iron deficiency anemia are relatively late findings.
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