Abstract
Thrombotic storm (TS) is a rare life-threatening entity that is characterized by multiple thrombotic events affecting diverse vascular sites occurring over a short period of time (days to weeks). We describe a case of a young boy who developed extensive and rapidly progressive thrombosis which required intensive treatment that included the use of triple antithrombotic therapy, pharmacomechanical thrombectomy, systemic thrombolytic therapy, and the combined use of plasmapheresis and immunosuppression.
Highlights
Thrombotic storm (TS) is a rare life-threatening entity that is characterized by multiple thrombotic events affecting diverse vascular sites occurring over a short period of time
We describe a case of a young boy who developed extensive and rapidly progressive thrombosis which required intensive treatment that included the use of triple antithrombotic therapy, pharmacomechanical thrombectomy, systemic thrombolytic therapy, and the combined use of plasmapheresis and immunosuppression
An inferior vena cava (IVC) filter was placed to prevent further pulmonary embolism (PE), after which the patient was transferred to the pediatric intensive care unit (PICU), where a continuous infusion of unfractionated heparin (UFH) was initiated
Summary
Thrombotic storm (TS) is a rare life-threatening entity that is characterized by multiple thrombotic events affecting diverse vascular sites occurring over a short period of time (days to weeks). TS: Thrombotic Storm; DVT: Deep Vein Thrombosis; PE: Pulmonary Embolism; IVC: Inferior Vena Cava; LMWH: Low Molecular Weight Heparin; ATIII: Antithrombin III; PICU: Pediatric Intensive Care Unit; UFH: Unfractionated Heparin; HITT: Heparin Induced Thrombocytopenia and Thrombosis; PNH: Paroxysmal Nocturnal Hemoglobinuria
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