Abstract

Calcifying epithelial odontogenic tumor (CEOT) is an uncommon, benign epithelial odontogenic tumor, first described in 1955 by Pindborg, with a locally aggressive behavior; it represents only 1% of the total odontogenic tumors. The origin of this locally invasive tumor remains unknown. It is thought to arise from stratum intermedium. It commonly affects the posterior mandible manifesting as a slow-growing asymptomatic swelling, often associated with an impacted tooth. The tumor usually occurs between the second and sixth decade of life and has no gender predilection. In this article we report a case of 73-year-old man with Pindborg tumor localized in lower right gum.

Highlights

  • IntroductionCalcifying epithelial odontogenic tumor (CEOT) is a rare and typically benign odontogenic lesion, with most common location in the mandibular premolar and molar region (68%) and, less frequently, in the maxilla. [1] [2]

  • Calcifying epithelial odontogenic tumor (CEOT) is a rare and typically benign odontogenic lesion, with most common location in the mandibular premolar and molar region (68%) and, less frequently, in the maxilla. [1] [2]CEOT can be divided into two clinico-topographic variants: Intraosseous or Extraosseous with an incidence of 94% and 6% respectively. [3]The term CEOT has been generally accepted and adopted by the WHO in the first edition of “Histological Typing of Odontogenic Tumors, Jaw Cysts, and Alied lesion”, where it was recognized as a distinct entity

  • According to WHO classification of 1992, CEOT is defined as a “locally invasive epithelial neoplasm characterized by the development of intra-epithelial structures, probably of an amyloid-like nature, which may be calcified and which may be liberated as the cells breakdown”. [7] CEOT is often asymptomatic and slow-growing ; the presence of symptoms is usually due to the mechanical compression of the tumor on the vital facilities; the lesion may cause pain, epistaxis, headache, nasal obstruction and stuffiness

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Summary

Introduction

Calcifying epithelial odontogenic tumor (CEOT) is a rare and typically benign odontogenic lesion, with most common location in the mandibular premolar and molar region (68%) and, less frequently, in the maxilla. [1] [2]. Calcifying epithelial odontogenic tumor (CEOT) is a rare and typically benign odontogenic lesion, with most common location in the mandibular premolar and molar region (68%) and, less frequently, in the maxilla. Pindborg first described it as a separate entity and he reported three cases, all male patients. A case of 73-year-old man with Pindborg tumor (CEOT) of gingival is described. 2. Case report A 73-year-old man presented in our hospital for gingival swelling. Case report A 73-year-old man presented in our hospital for gingival swelling He performed an orthopantomography showing an irregular mass in the right lower gingiva. The lesion was a represented by a 2x1.5x0.8 cm neoformation with a whitish area of 1.5x1 cm (figures 1). Stefania et al / GSC Biological and Pharmaceutical Sciences 2019, 09(03), 047–051

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