Abstract
BackgroundBony metastases were occasionally the initial presentations of malignancy. Overlooking of bony changes on radiographs in cancer patients with non-specific clinical symptoms may lead to delayed diagnosis.Case presentationWe presented a 70-year-old male having hypercalcemia and diffuse osteoblastic bone metastases on routine plain films. Finally, prostate cancer was diagnosed with a prostate needle biopsy.ConclusionAlthough the modern radionuclide bone scanning is useful in diagnosis, osteoblastic bone changes are occasionally seen in plain films, which are frequently overlooked. To avoid delayed diagnosis, bony structures should be carefully examined in all plain-film radiographs.
Highlights
Bony metastases were occasionally the initial presentations of malignancy
Conclusion: the modern radionuclide bone scanning is useful in diagnosis, osteoblastic bone changes are occasionally seen in plain films, which are frequently overlooked
Bony structures should be carefully examined in all plain-film radiographs
Summary
The modern radionuclide bone scanning is useful in diagnosis, osteoblastic bone changes are occasionally seen in plain films, which are frequently overlooked. Bony structures should be carefully examined in all plain-film radiographs. PSA: prostate-specific antigen; Tc-99m MDP: technetium99m methylene diophosphate; FDG-PET: positron emission tomography with 18F-2-deoxyglucose. A fully informed written consent was obtained form the patient family for the publication of this case and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal
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