Abstract
Unfractionated heparin is the most common anticoagulant used during percutaneous coronary intervention (PCI). Practice guidelines recommend an initial heparin bolus dose between 70 to 100 U/kg to achieve target activated clotting time (ACT) of 250-300 seconds. The relationship between heparin dose and ACT can significantly vary among individuals. The purpose of this study was to examine the dose distribution and effects of clinical comorbidities on anticoagulation.
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Schedule a callMore From: Journal of the Society for Cardiovascular Angiography & Interventions
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