Abstract
Graves' hyperthyroidism has a various number of well-recognized manifestations. Galactorrhea is a rare manifestation in this disease. We describe a 33-year-old man who presented with the symptoms of hyperthyroidism, gynaecomastia, and galactorrhea for 2 months. Physical examination revealed goitre, gynaecomastia, and galactorrhea, bilaterally. Laboratory investigations demonstrated high free thyroxine with suppressed thyroid-stimulating hormone level together with elevated anti-TSH receptor; therefore, the diagnosis of Graves' disease was confirmed. Other investigations to elucidate the etiology of galactorrhea were normal, so the galactorrhea was hypothesized to be caused by Graves' disease. The gynaecomastia and galactorrhea resolved with the successful treatment of hyperthyroidism. Although the galactorrhea is extremely rare in thyrotoxicosis male patients, to the best of our knowledge, this is the third case which reported gynaecomastia and galactorrhea in male patient who presented with thyrotoxicosis.
Highlights
Thyrotoxicosis is one of the possible causes of gynaecomastia and galactorrhea
We describe a male patient who presented with symptoms and signs of thyrotoxicosis together with gynaecomastia and galactorrhea
Thyrotoxicosis improved together with normal free thyroxin but thyroidstimulating hormone level remains suppressed (TSH 0.01, reference range 0.35–4.94 mIU/L); in parallel with the disappearance of the galactorrhea after treatment with methimazole for 3 months, the gynaecomastia disappeared after treatment for 5 months
Summary
Thyrotoxicosis is one of the possible causes of gynaecomastia and galactorrhea. The prevalence of gynaecomastia in thyrotoxicosis patients from two series [1, 2] has been reported as high as 40%. Galactorrhea has rarely been reported in Graves’ disease and mostly reported in women [3]. We describe a male patient who presented with symptoms and signs of thyrotoxicosis together with gynaecomastia and galactorrhea
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