Abstract

A 12-week-long randomized, double-blind, placebo-controlled, parallel-group comparison trial was conducted to determine the effects of long-term standardized bilberry extract (SBE) intake on tonic accommodation of ciliary muscle caused by visual display terminal (VDT) tasks. This study was compliant with the accordance with CONSORT 2010 statement. A total of 109 healthy adult men and women aged 20–60 years were recruited and randomized into SBE and placebo groups. The subjects in the SBE and placebo groups were administered 240 mg of SBE and placebo, respectively, once daily for 12 weeks. Tests were performed before and after VDT tasks at week 0, 4, 8, and 12; high-frequency component (HFC)-1 value was the evaluation outcome. Results showed that post-load HFC-1 values at weeks 8 and 12 were significantly improved in the SBE group than in the placebo group (p = 0.014 and 0.017, respectively). This study shows that oral consumption of 240 mg SBE extract for 12 weeks relieves the tonic accommodation of the ciliary muscle caused by VDT tasks and near-vision tasks.

Highlights

  • Owing to the increased distribution of visual display terminal (VDT) devices, our eyes are constantly being overworked [1,2]

  • high-frequency component (HFC) of accommodative microfluctuation measured before VDT loading

  • The subjects were recruited between January 18 and February 29, 2016, and the trial was conducted from April 11 to July 21, 2016

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Summary

Introduction

Owing to the increased distribution of visual display terminal (VDT) devices, our eyes are constantly being overworked [1,2]. Of the workers experiencing physical fatigue and VDT work-related symptoms, 91.6% experience “ocular fatigue and ocular pain,” indicating a high load of VDT tasks on the eyes [1]. The use of VDT devices, such as smartphones and tablets when used and placed close to the eyes, is rapidly spreading among people. Because individuals use VDT devices, such as personal computers and smartphones, close to their eyes for long periods of time, the eye muscles become fatigued and experience tension, making focus adjustment difficult. Because more and more young people are starting to experience symptoms similar to presbyopia, it is extremely important to prevent and reduce ocular fatigue to improve the quality of life of VDT users

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