A 12‐country assessment of body adiposity in Latin American children and its association with cardiometabolic risk factors (1031.3)

Abstract

Aims: (1) To assess body adiposity in Latin American (LA) children using the deuterium oxide dilution (D2O) method; (2) to evaluate the association of these results with indices of cardiometabolic risk; and (3) to correlate D2O‐measured adiposity with traditional measures of body size. Methods: 1,205 6‐12 year old children (547 males and 658 females) from 12 LA countries taking part in IAEA Technical Cooperation project RLA6064. Percent body fat was estimated by D2O (%BF‐D2O). Anthropometric measurements and cardiometabolic indices were collected. Multiple linear regressions were used to model the relationship between cardiometabolic indices and %BF‐D2O. Spearman’s correlations estimated the association between %BF‐D2O with adiposity by skinfolds equations and BMI. Results: Females displayed significantly greater %BF‐D2O than males (p<0.05), with a diverse range of adiposity in the age range covered. Regression analyses confirmed the significant association of %BF‐D2O with TC, HDL, LDL, Insulin, HOMA‐IR, CRP, IL‐6, HCT, SBP and DBP. Spearman’s correlation revealed a stronger association between %BF‐D2O and Dezenberg or Deurenberg skinfold formulas (rho=0.82 and 0.88) compared with BMI (rho=0.69). Conclusions: %BF‐D2O measurements demonstrated a wide range of adiposity, with significant differences between countries, age and sex, and a significant association with cardiometabolic indices.*On behalf of the RLA6064 project coordinatorsGrant Funding Source: Technical Cooperation Fund of the IAEA and local resources in each participating country