A 10-year retrospective, clinicopathological study of 2100 ovarian lesions in a rural medical college hospital of West Bengal, India

Abstract

Background: Distribution of the different ovarian cancers has been widely studied in Western countries. However, such studies are limited in West Bengal of India, especially in rural areas. The aim was to study the distribution of morphological pattern of benign, malignant, and nonneoplastic ovarian lesions and bilateral involvement in different morphologic subtypes. The study was also aimed to observe different clinical presentations in ovarian lesions. Methods: A retrospective study from August 2009 to July 2019 was undertaken. A total of 2100 surgical specimens of ovaries were analyzed. Detailed clinical information and radiological findings were recorded from patients' case history sheets. Results: Of 2100 cases, benign ovarian lesions were found in 1491 cases (71%), malignant in 252 cases (12%), and nonneoplastic in 357 cases (17%). Serous cystadenoma was 41.45% of all benign tumors (618/1491 cases), followed by mucinous cystadenoma (22%, 328/1491 cases) and mature cystic teratoma (18.44%, 275/1491 cases). Among the malignant cases, highest bilaterality was seen in serous cystadenocarcinomas (41.30%) and among benign tumors in endometrioid tumors (27.58%). Bilateral follicular cysts were found in 35.21% cases among nonneoplastic diseases. Conclusion: Earlier presentation of malignant tumors was observed. Lower percentage of endometrioid carcinoma was also noted compared to other studies. The most common primary ovarian tumor with bilateral involvement was serous cystadenocarcinoma (41.30%) followed by endometrioid adenocarcinoma (33.33%).