Abstract
Background: The staging of non-small cell lung cancer(NSCLC)to detect mediastinal lymph node(MLN) metastases is very important for determining the therapeutic strategy. Methods: Twenty-three patients with proven NSCLC were enrolled in this study. All of the patients underwent chest computed tomography(CT)and(superscript 99m)Tc-tetrofosmin chest single photon emission computed tomography(SPECT)preoperative staging. MLN metastases were determined on the basis of postoperative pathologic findings to compare the diagnostic accuracy of chest CT with that of(superscript 99m)Tc-tetrofosmin chest SPECT. Results:(superscript 99m)Tc-tetrofosmin chest SPECT showed a diagnostic accuracy rate of 91.3% in detecting MLN metastases. Chest CT had an accuracy rate of 69.6%.Conclusion:(superscript 99m)Tc-tetrofosmin chest SPECT was more accurate than chest CT in detecting MLN metastases in NSCLC patients.
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