996 Impact of Extremes of BMI on Outcomes Following Lung Resection

Abstract

Abstract Aim Body Mass Index (BMI) has been shown to be an independent predictor of survival following lung resection for non-small cell lung cancer. This study aimed to quantify the short-term impact of abnormal BMI on outcomes following all lung resections. Method Lung resections at UHNM were examined from 01/01/2012 to the 07/07/2021. Variables were extracted from a retrospective database. Patients were divided into three cohorts: low BMI (<18.5), normal/high BMI (18.5–29.9) and obese BMI (>30). Post-operative complications, length of stay and 30-day mortality were examined. Results 2439 patients were identified. 2341 BMI values were available and included. 2.6% (n=60) had a low BMI, 67.7% (n=1586) had a normal/high BMI and 29.7% (n=695) had obese BMI. Post-operative complications were found to be higher in the low BMI group (43.3%) when compared to a normal/high and obese BMI group (30.8% and 23.2%, respectively). Length of stay was higher in the low BMI group (10.2 days) compared with normal/high or obese BMI group (7.5 and 6.3 day, respectively). 30-day mortality was higher in the low BMI group (8.3%) compared with the normal/high and obese BMI group (2.0% and 1.7%, respectively). Conclusions Low BMI is associated with significantly worse immediate post-operative outcomes and approximately a four-fold increase in mortality when compared with obese BMI. Obesity appears to incur a protective effect in mortality.