Abstract

Dostarlimab is a humanized programmed death 1 (PD-1) receptor monoclonal antibody that blocks interaction with the ligands PD-L1 and PD-L2. GARNET is a phase I study assessing antitumor activity and safety of dostarlimab monotherapy in patients with solid tumors. Here we report TRAEs across cohort A1 (mismatch repair–deficient [dMMR] endometrial cancer [EC]), cohort A2 (mismatch repair–proficient [MMRp] EC), cohort E (non–small cell lung cancer [NSCLC]), and cohort F (dMMR non-EC) of the GARNET trial.

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