986 Acute Post Streptococcal Glomerulonephritis in Children

Abstract

Aim of the study: To present a number of children with set diagnosis of APSGN in the Pristina Children's Clinic, incidence, clinical characteristics of the disease an adequate treatment. Their follow up aimed to determine the further course of the disease and the possibility for progressing into a chronic form. Materials and Methods: This was an analysis of the children treated in the Prishtina Children's Clinic during 2007-2009. The diagnosis of APSGN was set in 132 children based an anamnestic date for existing a prior streptococcal infection, clinical picture, as well as laboratory analyses. Results: The dominant age group was 7-11 year olds, while male patients were more frequent. Anticipatory throat infection appeared in 82% of all cases. In all cases, the clinical symptoms were hematuria and/or proteinuria. Hypertension was present in 73% cases, while edema was confirmed in 79 % of hospitalized patients. Positive ASO was confirmed in 75,8%. All cases were treated successfully and regularly followed up, only 3,5% cases were found resistant to therapy and progressed to chronic form. In all chronic cases, the diagnosis was confirmed after a renal biopsy. Conclusion: In a 96,5% of patient a complete recovery was obtained with further outpatient follow up, and only 3,5 % entered into the form of chronic glomerulonephritis.