985 PREDICTION OF PERIOPERATIVE OUTCOMES OF PARTIAL NEPHRECTOMY: COMPARISON BETWEEN RENAL AND PADUA SCORES

Abstract

INTRODUCTION AND OBJECTIVES: To compare RENal and PADUA scores to predict major complications (Clavien 3-4), conversion to radical nephrectomy and warm ischemia time in patients undergoing partial nephrectomy for renal tumor. METHODS: We retrospectively reviewed the files of 177 patients scheduled in our center for a partial nephrectomy for a single renal tumor. Surgical outcomes, including perioperative complications, as well as renal and oncological outcomes were analyzed by Wilcoxon rank sum and Chi-square test, as appropiate. Then, ROC curves were constructed to compare the predictive accuracy of both scores for major complications, conversion to radical nephrectomy and warm ischemia time. RESULTS: Among the 177 patients, 55 were female and median age was 55.0 /12.8 (range 23 80). Median scores were 7 (4-11) for RENaL and 8 (6-13) for PADUA. In multivariate analysis both RENaL and PADUA scores were predictor conversion to radical nephrectomy (n 29 ; p 0.006 for RENaL and p 0.013 for PADUA) and warm ischemia time more than 20 minutes (n 62 ; p 0.005 for RENaL and p 0.013 for PADUA). But RENaL and PADUA score failed to predict major complications (n 21 ; p 0.91 for RENaL and p 0.93 for PADUA). By comparing ROC curves, PADUA and RENaL scores were comparable to predict the occurence of conversion to radical nephrectomy (p 0.70) a warm ischemia time more than 20 minutes (p 0.68) and major complications (p 0.63). CONCLUSIONS: In our series, RENaL score and PADUA score are comparable to predict the risk of conversion to radical nephrectomy, major complications or a long warm ischemia time. These results must be confirmed by a prospective study.