Abstract

Immunotherapy has been one of the most important developments in cancer treatment of the past few decades. With the inclusion of immunotherapy in cancer treatment, overall survival rates have increased in some cancers. However, its usage comes with harmful side effects and research has shown that concomitant use of antibiotics has decreased its efficacy. Hence, our study aims to evaluate the risks and benefits of using pembrolizumab with or without concomitant use of antibiotics, in which such evidence can be used for the development of biomarkers for immunotherapy treatment in the future.

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