968 LEARNING CURVE IN SALVAGE PROSTATE WHOLE GLAND CRYOTHERAPY: UPDATE FROM THE COLD REGISTRY

Abstract

You have accessJournal of UrologyProstate Cancer: Advanced (III)1 Apr 2013968 LEARNING CURVE IN SALVAGE PROSTATE WHOLE GLAND CRYOTHERAPY: UPDATE FROM THE COLD REGISTRY Philippe E Spiess, Michael L Cher, and J Stephen Jones Philippe E SpiessPhilippe E Spiess Tampa, FL More articles by this author , Michael L CherMichael L Cher Detroit, MI More articles by this author , and J Stephen JonesJ Stephen Jones Cleveland, OH More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.549AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES In the present study, we assessed whether there is a learning curve in the reported outcomes of prostate whole gland salvage cryotherapy across academic and community centers gathered within the COLD registry. METHODS A prospectively, centrally collected secure online database has been developed of patients undergoing salvage whole gland cryoablation (N=728). A total of 39 participating centers participated within the COLD registry. For the purposes of this study, low (N=19) and high volume (N=20) centers were defined as facilities participating within the COLD registry who had conducted < 20 or > 20 successive prostate whole gland salvage cryoablation procedures as gathered within the COLD registry. RESULTS Although there were no reported differences between low and high volume centers with regards to the incidence of urinary retention (P=0.13) and urethrocutaneous fistulas (P=0.11), we did note that high volume centers had improved biochemical failure rates using the Phoenix definition (P=0.04), potency rates (P=0.004), and post-treatment biopsy rates (P=0.02). CONCLUSIONS The present study highlights that there in fact exists a learning curve in the treatment related outcomes of prostate whole gland salvage cryotherapy although this could result from improved patient selection and/or cryoablative skills. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e398 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Philippe E Spiess Tampa, FL More articles by this author Michael L Cher Detroit, MI More articles by this author J Stephen Jones Cleveland, OH More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...