96/03245 - Indoor radon from building material remedial action using adsorptive wallpapers

Abstract

Osteoarthritis (OA) is the most common joint disease and is reported to be seen first in the foot at an early age. While there have been controlled comparison studies of non-steroidal anti-inflammatory medications (NSAIDs) in the treatment of OA, these are mostly limited to the knee and hip. This randomized, double-blind parallel trial of 8 weeks duration compared piroxicam (Feldene, 20 mg daily) to ibuprofen (Mortin, 1800 mg daily) in the treatment of symptomatic OA of the foot in 39 patients. No statistically significant differences were reported, and both groups experienced pain relief and increased mobility. No serious adverse events occurred during the study and laboratory parameters showed no clinically relevant changes in either treatment group. The study suggests that piroxicam and ibuprofen are efficacious and equally appropriate choices in the treatment and management of pedal OA.