Abstract
EAS June 2011 Cardiovascular disease (CVD) is a multifactorial disorder depending on both genetic and environmental factors. Low density lipoprotein (LDL) comprises a heterogeneous population of particles in terms of size, biochemical properties and atherogenic potencial. Several studies have demonstrated that small dense LDL (sdLDL) particles are an emerging cardiovascular (CV) risk factor due to its atherogeneicity. The objective of this study was the measurement of sdLDL in patients with genetic diagnosis of Familial Hypercholesterolaemia (FH) and clinical diagnosis of Familial Combined Hyperlipidaemia (FCHL) to establish a relation between sdLDL, CV risk and the efficacy of therapeutics. Background
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