Abstract

NPC is an Epstein-Barr virus (EBV)-associated disease. EBV plays a pivotal role in tumor initiation and progression. It is well known that immune-suppression contribute to the initiation and progression of NPC and the immune function is correlated with the prognosis of NPC patients. However, the association of EBV infection status with peripheral immune parameters and clinical outcome in patients with advanced NPC is still not fully clear.

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