Abstract
The aim of the research is to analyze clinical-genetic parameters of health in children living in regions with various ecological troubles for elaboration of optimum methods of combined chronic pathology and chromosomal damages development forecast. This research is devoted to health examination of 120 children living in the region of the Semipalatinsk nuclear ex-range, 203 children living in the Aral Sea region (the basic groups) and 100 children living in the region of relevant well being (control group), aged 7-15 y. Children underwent complex clinical, functional and instrumental health examination, account of minor anomalies of development (MAD) and cytogenetic investigation. Three and more chronic diseases are diagnosed in children from the Semipalatinsk nuclear ex-range and from the Aral Sea region authentically more often than in control group. The prevalence of urinary system diseases and lungs pathology is determined in group from the Aral Sea region. Incidence of congenital malformations of development considerably doesn't differ in children from the Semipalatinsk nuclear range and from the Aral Sea region. The general incidence of chromosomal aberrations is 1,86±0,09 in children from the Semipalatinsk nuclear ex-range and 1,90±0,09 - from the Aral Sea region, that is three times more often than in control group (0,62±0,07). Correlation between the level of MAD and quantity of chronic diseases in the Aral Sea region is r=0,91- 0,96 and in the Semipalatinsk region is r=0,86-0,96. Correlation between the level of MAD and level of chromosomal aberrations in the Aral Sea region is r=0,99 and in the Semipalatinsk is r=0,99.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
