Abstract
Skin and soft tissue infections are considered by location, depth of infection, etiologic agent, and clinical setting and may result from either primary cutaneous inoculation or, less commonly, hematogenous seeding. Most cutaneous infections are not associated with bacteremia, and diagnosis and empirical therapy are based on physical findings and clinical setting. Significant skin and soft tissue infection may occur throughout the age spectrum. Minor local trauma as the initial pathogenic event is a common feature of these processes. Although invasive infections may occur in previously healthy individuals, many systemic risk factors predispose individuals to these infections. Good hygienic practices and attention to early therapy for superficial processes such as dermatophyte infection reduce the risk for progressive cutaneous and soft tissue infection. Individuals with recurrent cellulitis may benefit from chronic antibiotic suppression.
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More From: Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
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