927-P: Risk of Substance Use Disorders among Adolescents and Emerging Adults with Type 1 Diabetes: A Population-Based Cohort Study

Abstract

Introduction: Adolescents and young adults with chronic health conditions such as type 1 diabetes mellitus (T1D) are more likely to engage in high-risk behaviors. Previous studies regarding substance use are mostly derived from cross-sectional studies and are limited by lack of population-based comparison groups. In addition, despite the rising popularity of vaping, little is known about the incidence of vaping in adolescents and young adults with T1D. Objective: We explored the incidence of substance use disorders (SUD) and vaping in adolescents and emerging adults with T1D compared to age and gender matched nondiabetic referents residing in Olmsted County, Rochester, MN. Methods: People (12-25 yrs) with T1D (n=230) were matched 1:2 to referents (n=460), resulting in a total of 984 person-years of available data. SUD and vaping were ascertained using ICD-9/r ICD-10 codes from a population-based records-linkage system of patient records for Olmsted County, Minnesota residents. Results: Risk of incident SUD diagnosis rates were higher in those with T1D compared to matched referents with alcohol, marijuana, and smoked tobacco being most common. When stratified by gender, results were similar in males, but not females. Conclusion: Our findings confirm the critical need for substance use screening and mental health support for adolescents and emerging adults with T1D. Disclosure A. Creo: None. S. Sriram: None. L. Vaughan: None. A. Weaver: None. S. Kumar: Consultant; Self; Rhythm Pharmaceuticals, Inc.