Abstract
Much attention has been paid to the effects of weight reduction on protein and carbohydrate metabolism. However, only few reports exist in regards to vitamin status during weight reduction in obese adolescents. Therefore we investigated serum Vitamin A, E, and C (HPLC), retinol binding protein (RBP, RID), prealbumin (PA, RID), and LDL-C LRC-methods) in 16 obese adolescent boys (45±11% overweight, 12.1±1.2 years, mean±SD) during a 3 week diet camp and after 6 months follow up. Weight loss after 3 weeks: 5.3±1.3 kg, weight gain after 6 months:2.3±1.9 kg (1.3±11.9% overweight). Vitamin A and E blood levels markedly decrease after 3 weeks but reached baseline levels 6 months later. Concomitantly RBP and PA showed similar changes, Vit.E an analgous drop and rise. Vitamin C levels remained unaffected. The low vitamin A and E concentrations during the 3 weeks treatment (11 of 21 boys could be classified as “high risk for deficiency”) can be explained by the marked fall of RBP and PA, due to the cetabolic situation, inspite of adequate protein intake (0.9±0.2g/kg ideal body weight). We therefore suggest that rather the low concentrations in trans-Dortproteins than impaired vitamin intake caused these effects.
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