Abstract

TQ-B3101 is a novel small molecule receptor tyrosine kinase inhibitor, which targets to ALK, ROS1 and MET. Preclinical studies showed that it had a good tumor inhibition activity and duration. This study aims to evaluate the efficacy and safety of TQ-B3101 monotherapy in the first-line treatment in patients with ROS1-positive non-small cell lung cancer (NSCLC).

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