Abstract
The usual semiotic sign of motor neuron damage is hypotrophy of target muscle. However, in rare cases, a motor neuron damage results in hypertrophy: this is principally due to a chronic triggering of spontaneous activity in affected motor units, with continuous or subcontinuous activation of target muscular fibers. Muscular neurogenic hypertrophy was reported during radiculopathy, mononeuropathy, focal myelopathy, tethered cord syndrome, chronic inflammatory demyelinating polyneuropathy. In this report we present classification of muscular neurogenic hypertrophy, based on topography, etiology and type of spontaneous activity possibly observed. We present also two cases: the first one due to spondyloarthrosis associated with T11–T12 discopathy, the second one due to ischiatic nerve neuropathy related to proximal femur fracture.
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