870P Comparison of PD-L1 and VISTA expression levels in head and neck cancers in primary and recurrent tumor tissue after radiotherapy/chemoradiotherapy

G Yazıcı Şener,O Sutcuoglu,B Öğüt,D.C Guven,A Kavuncuoğlu,A Özet,N Özdemir,Y.G Güler Tezel,N Akyurek,O Yazıcı

doi:10.1016/j.annonc.2021.08.1280

870P Comparison of PD-L1 and VISTA expression levels in head and neck cancers in primary and recurrent tumor tissue after radiotherapy/chemoradiotherapy

G Yazıcı Şener, O Sutcuoglu + Show 8 more

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https://doi.org/10.1016/j.annonc.2021.08.1280

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Journal: Annals of oncology : official journal of the European Society for Medical Oncology	Publication Date: Sep 1, 2021
License type: publisher-specific-oa

Affiliation: Gazi University, Hacettepe University

#Recurrent Tumor Tissue #Neck Cancers + Show 8 more

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Abstract

PD-L1 and VISTA are thought to play a role in escape from the immune system, tumor progression and treatment response in tumoral tissue. It has been suggested that radiotherapy may increase the expression levels of immune biomarkers. The current study aimed to evaluate the effects of radiotherapy (RT) and chemoradiotherapy (CRT) on PD-L1 and VISTA expression in head and neck cancers.

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