Abstract

Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma (CTCL), is characterized by malignant T-cell skin infiltration that leads to inflammation and skin barrier defects. Identifying reproducible biomarkers in MF skin is important for monitoring disease activity. Skin tape-stripping is gaining recognition as a non-invasive, easy method for tracking disease biomarkers. Tape strips from lesional (L) and non-lesional (NL) skin of 42 MF patients and matched sites of 21 healthy controls (HC) were analyzed with a proximity extension assay of 183 proteins relevant to oncology and inflammation.

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