Abstract
Merkel cell carcinoma is an aggressive neuroendocrine tumor of the skin. Phenotypes include a low mutation and high mutation variant. Standard of care treatments for MCC include cytotoxic chemotherapy and immune checkpoint inhibitors. Presently, there are no targeted therapy options for MCC, however the AACR Project Genie is a large multi-institutional international database of genomic samples of tumors uniquely suited to evaluate rare tumors.
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