Abstract

Purpose To investigate the factor associated with survival after DEB TACE in 366 patients (pts) with unresectable HCC. Materials and Methods Consecutive patients with unresectable HCC who received DEB TACE over last 82 months were studied. Survivals were analyzed according to different parameters from the time of 1st DEB TACE. Kaplan Meier estimator by log rank test and Cox proportional Hazard model (for multivariate analysis) were used survival analyses. Results 366 patients (mean 61.1 years, SD 10.4) were included in this study. Median overall survivals (OS) from diagnosis and from DEB TACE were 24.1 months (m) and 19.5 m respectively. Child-Pugh Class A, B and C stage were present in 55.2%, 38.5% and 6.3% of the pts with corresponding median OSs were 36.6m, 19.5m and 6.7 m respectively (p 10cm were present in 69.1%, 19.4% and 11.5% of the pts with corresponding median OSs were 25.6m, 9.4m and 5.6m respectively (p Conclusion Child-Pugh class, tumor size, ECOG PS, PVT, metastasis, and serum AFP level are significant independent predictor of survival after DEB TACE treatment. Table 1

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