Abstract
The brain is a plastic and vulnerable organ of the body. Experiences cause adaptive changes in dendrite length and branching, turnover of spine synapses and neurogenesis in the dentate gyrus region of the hippocampal formation. This adaptive plasticity is mediated by the excitatory amino acid neurotransmitter, glutamate, acting in concert with endogenous mediators such as neurotrophic factors, endogenous acetyl-L-carnitine (LAC) and other cellular messengers, along with circulating hormones.
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