Abstract
other sites (incidental TICs) were excluded from this analysis. Daily fiber & abstinence from ASA & NSAIDs were recommended. Outcomes were analyzed for PRES vs. DEF subgroups & by baseline treatment groups (MED, ENDO, SURG) post-60 days after initial diagnosis & treatment. Data were recorded on standard forms by research coordinators & SAS was used for data management & analysis. RESULTS: Patients were similar in all demographics, except for more RBC's & ENDO treatments in the DEF group. The mean age was 72 yrs, 29% were female, 16% took anticoagulants & all had co-morbidities. 43 pts (37.7%) had definitive & 71 pts (62.3 %) presumptive TIC Bleeds. Mean F/U was 1195±77 days. Compliance with fiber & ASA/NSAIDs was low. The rates of rebleeds & other TIC COMPL for DEF (N=43) vs. PRES (N=71); & MED (N=74), ENDO (N=32) & SURG (N=8) are shown in the Table. No differences were significant (p> 0.05). The cumulative death rate was 16.7% & no one died of TIC bleed or TIC-COMPL. CONCLUSIONS: For patients with documented diverticular hemorrhage followed long-term: 1. Rebleeding rates were low, but as likely to be from TICs as other GI sites. 2. No one died of TIC bleeds or TIC complications, which were also very rare. 3. There were no significant outcome differences after medical, endoscopic, or surgical therapies. Based upon these data, the recommendation of surgery for an index diverticular bleed should be revised. Partially supported by NIH grants (K24DK002650) & CURE (P30-DK040301) Human Studies Core.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have