Abstract
AbstractThe complex cis‐[Pt(NH3)282Br2] has been prepared as a possible model for cisplatin, cis‐[Pt(NH3)2Cl2]. The stability of cis‐[Pt(NH3)282Br2] was investigated in 0.9% saline solution and sterile water. In both cases the 82Br label was rapidly displaced in the first hour (t1/2 = 73 min and 96 min respectively). Thus, cis‐[Pt(NH3)282Br2]cannot be used for determining the fate of the labile ligands of cisplatin.
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More From: Journal of Labelled Compounds and Radiopharmaceuticals
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