828 Factors Influencing Periprocedural Stroke at the Time of Transcatheter Aortic Valve Implantation in the Era of Cerebral Protection

Abstract

To compare patient factors in those who suffer periprocedural stroke at the time of transcatheter aortic valve implantation (TAVI), with a view to identifying patients who may benefit from provisional cerebral protection device use. We reviewed 523 patients who underwent TAVI at a single centre between 2008 and 2019. All statistics were performed in SPSS. 22 (4.2%) had radiologically-proven cerebrovascular accident associated with their TAVI procedure. In 27 valve-in-valve procedures in this cohort, there was no periprocedural stroke events. Table 1 describes the patient characteristics that were associated with increased risk of stroke. Logistic regression was performed to generate odds ratio (OR). There was a trend to increase risk associated with CKD and BMI>30 patients although these results did not reach statistical significance. There was a trend towards increased risk of periprocedural stroke in patients undergoing TAVI who had a BMI>30 and chronic kidney disease. These patients may benefit from the consideration of a cerebral protection device.Table 1Odds ratios of patient characteristics associated with periprocedural stroke at the time of TAVI.Stroke (n=22)All others (n=497)ORP valuePatient characteristicsAge at TAVI (years)82.783.41.010.801Female13 (59%)214 (42.7%)1.50.476BMI > 309 (40.1%)89 17.9%)3.30.06Hypertension12 (54.5%)248 (50.4%)1.20.811Diabetes6 (27.3%)112 (22.8%)1.10.863Chronic kidney disease (CKD)5 (22.7%)70 (14.2%)2.30.227Dialysis1 (4.5%)7 (1.4%)3.40.381PAD2 (9.1%)19 (3.8%)1.80.614 Open table in a new tab