Abstract

Background: Safe management of T1D in congregate settings such as diabetes camps may involve continuous glucose monitoring (CGM) devices, and managers of these facilities face choices regarding systems and deployment strategies. We aimed to compare individual versus multiplex monitoring strategies and to separately compare CGM systems from Dexcom (G6) and Abbott (Libre Pro) . Methods: G6 users included 45 campers ages 8-17 years. Four used individual SMBG with G6 Pro systems in blinded mode; 41 used unblinded G6 systems whose data were available for remote review on an investigational multiplex display. Separately, data from 17 campers using G6 systems were compared to data from 17 campers using Libre Pro systems. Results: As shown in the Table, most metrics of glycemic control favored the multiplex-monitored group over the individually SMBG-monitored group; the between-groups difference reached statistical significance with respect to nocturnal percent of time <54 mg/dL (%<54) . Analysis of data from G6 and Libre Pro systems revealed significantly lower mean glucose levels and more hypoglycemia among Libre Pro users, especially at night. Conclusion: Meaningful differences in CGM-measured overall and nocturnal hypoglycemia may result from choices in monitoring strategies and device manufacturers. Disclosure S. E. Gleich: Research Support; Dexcom, Inc. H. R. Tecca: Employee; Dexcom, Inc. N. D. Gibson-north: n/a. E. Schuster: Employee; Dexcom, Inc. C. R. Green: Employee; Dexcom, Inc. T. C. Walker: Employee; Dexcom, Inc., Stock/Shareholder; Dexcom, Inc. Funding Dexcom, Inc.

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