Abstract

There are more than a quarter million episodes of acute uncomplicated pyelonephritis (AUP) among adult women in the United States each year. To determine the optimal selection and duration of antimicrobials, these authors conducted a randomized, double-blind, multicenter trial comparing a 7-day oral ciprofloxacin (CF) regimen and a 14-day trimethoprim-sulfamethoxazole (TMP-SMX) regimen in 255 premenopausal …

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