785-5 Color Doppler M-Mode Velocity Propagation: An Index of Early Left Ventricular Filling That Combined with Pulsed Doppler Peak E Velocity may Predict Left Atrial Pressure

Abstract

The propagation velocity of transmitral flow (MVP). as defined by color Doppler M-mode, has recently been proposed as an index of ventricular relaxation. Left atrial pressure, relaxation and left ventricular contractility are the main determinants of peak E wave To assess the possibility of estimating left atrial pressure using pulsed Doppler peak E wave velocity and color Doppler IMVP). we studied 27 patients in the coronary care unit. Methods Peak early filling velocity IE) was measured using pulsed Doppler, while the slope of the color Doppler M-mode (S)was used to define mitral flow velocity propagation. All patients had a pulmonary artery catheter and pulmonary capillary wedge pressure was measured. The dimensionless ratio E/S (range 092–3.74) was significantly related to left atrial pressure (r = 0.74, P < 0.001). and provided a good predictor for left atrial pressure (LAP = 4.4 + 5.3E/S, SEE = 3.7 mmHg). S (37.2 ± 12.2 m/sec) was significantly lower than E(73.5 ± 26.3). p < 0.001, with no correlation between these velocities (r = 0.24). E was weakly correlated with LAP (r = 0.53, P = 0.005), while S showed a negative correlation (r = -0.325, P = NS). 1) The ratio of component velocity (E) over propagation velocity (S) of early ventricular filling wave can provide an good estimate of left atrial pressure. 2) Transmitral flow velocity propagation is independent of the component velocities of the E wave, 3) S is not related to LAP.